Hotel S. Anna
From
$216
/ night
Select dates to see prices and availability
From
$216
/ night
About this property
Take in the views from a garden and make use of amenities such as complimentary wireless internet access and concierge services.
Amenities
Take in the views from a garden and make use of amenities such as complimentary wireless internet access and concierge services.
Business amenities
Featured amenities include a 24-hour front desk and luggage storage.
Dining
Buffet breakfasts are available daily from 7:00 AM to 10:00 AM for a fee.
Rooms
Make yourself at home in one of the 20 guestrooms featuring minibars and flat-screen televisions. Complimentary wireless internet access is available to keep you connected. Bathrooms have complimentary toiletries and bidets. Conveniences include safes and desks, as well as phones with free local calls.
Location
With a stay at Hotel Sant' Anna, you'll be centrally located in Rome, just a 3-minute walk from St. Peter's Square and 6 minutes by foot from St. Peter's Basilica. This hotel is 0.7 mi (1.1 km) from Vatican Museums and 0.3 mi (0.5 km) from Sistine Chapel.
What's nearby
St. Peter's Square(0.1 miles)
Via Cola di Rienzo(0.2 miles)
St. Peter's Basilica(0.3 miles)
Sistine Chapel(0.3 miles)
Apostolic Palace(0.4 miles)
Tiber River(0.4 miles)
Corso Vittorio Emanuele II(0.5 miles)
Governor's Palace of the Vatican City State(0.5 miles)
Castel Sant'Angelo(0.5 miles)
Via Giulia(0.5 miles)
Bambino Gesu Hospital(0.6 miles)
Janiculum Hill(0.7 miles)
Vatican Gardens(0.7 miles)
Vatican Museums(0.7 miles)
Villa Doria Pamphili(0.8 miles)
Ciampino Airport (CIA)(22.2 miles)
Fiumicino - Leonardo da Vinci Intl. Airport (FCO)(18.7 miles)
Airport shuttle
Non-Smoking Rooms
Housekeeping
Safe-Deposit Box
Garden
Luggage Storage
Location
Borgo Pio 133, Rome, Italy
St. Peter's Square (0.1 miles)
Via Cola di Rienzo (0.2 miles)
St. Peter's Basilica (0.3 miles)
Sistine Chapel (0.3 miles)
Apostolic Palace (0.4 miles)
Tiber River (0.4 miles)
Room options
7
Basic Double Room
Room details
1 Queen Bed
Sleeps 2
172 ft²
Air ConditioningWi-Fi (Free)Private Bathroom
14
Classic Quadruple Room
Room details
1 Queen Bed
and 2 Twin Beds
Sleeps 4
301 ft²
Air ConditioningWi-Fi (Free)Private Bathroom
15
Classic Triple Room
Room details
1 Full Bed
and 1 Twin Bed
Sleeps 3
269 ft²
Air ConditioningWi-Fi (Free)Private Bathroom
18
Classic Double Room, 1 Bedroom
Room details
1 Queen Bed
Sleeps 2
194 ft²
Air ConditioningWi-Fi (Free)Private Bathroom
11
Double Room Single Use
Room details
1 Queen Bed
194 ft²
Air ConditioningWi-Fi (Free)Private Bathroom
Guest reviews of Hotel S. Anna
9.3
Superb
Based on 415 verified reviews
Who stays here?
Business
8%
Couple
36%
Family
36%
Group
12%
Solo
5%
What guests think
AI-generated summary based on recent guest reviews
At Hotel S. Anna, travelers highlight a prime Vatican-side location on lively Borgo Pio, consistently warm, helpful service, and clean, comfortable rooms within a charming historic building, creating an easy base for sightseeing and dining nearby.
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What guests think
At Hotel S. Anna, travelers highlight a prime Vatican-side location on lively Borgo Pio, consistently warm, helpful service, and clean, comfortable rooms within a charming historic building, creating an easy base for sightseeing and dining nearby.
Several guests during warmer periods reported the air conditioning was switched off seasonally, leading to warm rooms and occasional street noise when windows stayed open. Breakfast earns frequent praise, though a few found it average; overall, a characterful boutique stay.
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AI-generated summary based on recent guest reviews
Facilities
Not enough information in reviews.
Related guest reviews
10
John
Jun 10, 2024
·
Stayed 6 nights
Sant'Anna is lovely. We had a wonderful stay in this beautifully presented 16th century hotel. Our room was even better than described online. It is very close to the Vatican and only a few minutes stroll from St Peter's. The hotel staff are all really professional and friendly. Marcello made us most welcome and took care of everything we asked about. We loved meeting Nina the dog who calmly dozes near reception and gracefully brings a cozy ambience to the hotel! One of the nicest hotels we've ever stayed in.
Sant'Anna is lovely. We had a wonderful stay in this beautifully presented 16th century hotel. Our room was even better than described online. It is very close to the Vatican and only a few minutes stroll from St Peter's. The hotel staff are all really professional and friendly. Marcello made us most welcome and took care of everything we asked about. We loved meeting Nina the dog who calmly dozes near reception and gracefully brings a cozy ambience to the hotel! One of the nicest hotels we've ever stayed in.
10
Richard
Jan 2, 2025
·
Stayed 3 nights
Best room we've had in my entire 11 nights tour in Italy where we stayed in 5 other hotels before arriving at Sant' Anna hotel. Size of room was big (relative to the other rooms elsewhere), and the room deco had a "wow" effect when we opened the door. Best of all, lots of table space to place luggage, lots of clothes hangers and functional amenities. Though its elevator was small, the other hotels we went to elsewhere was equally small though it is not as ancient as Sant' Anna. Its proximity to Vatican and the shopping areas was excellent.
Best room we've had in my entire 11 nights tour in Italy where we stayed in 5 other hotels before arriving at Sant' Anna hotel. Size of room was big (relative to the other rooms elsewhere), and the room deco had a "wow" effect when we opened the door. Best of all, lots of table space to place luggage, lots of clothes hangers and functional amenities. Though its elevator was small, the other hotels we went to elsewhere was equally small though it is not as ancient as Sant' Anna. Its proximity to Vatican and the shopping areas was excellent.
10
JANICE
Sep 2, 2024
·
Stayed 8 nights
This hotel is a beautiful hotel built in the 16th century. Very close to the Vatican and many other historical sites. Many dining options. The people at the front desk were very helpful for any thing we needed. Highly recommend this hotel!
This hotel is a beautiful hotel built in the 16th century. Very close to the Vatican and many other historical sites. Many dining options. The people at the front desk were very helpful for any thing we needed. Highly recommend this hotel!
8
Michael
Apr 17, 2025
·
Stayed 1 night
We booked this hotel as it was close to Vatican City and was a recommendation. We enjoyed the hotel. No restaurant or bar but they exist in abundance within walking distance. The one issue for us was no AC and we were facing the busy pedestrian/cafe area and had to keep window open but lights and noise were an issue. Desk staff was very helpful giving directions and scheduling a car for us.
We booked this hotel as it was close to Vatican City and was a recommendation. We enjoyed the hotel. No restaurant or bar but they exist in abundance within walking distance. The one issue for us was no AC and we were facing the busy pedestrian/cafe area and had to keep window open but lights and noise were an issue. Desk staff was very helpful giving directions and scheduling a car for us.
10
Robert
May 25, 2024
·
Stayed 3 nights
Hotel is convenient as to is very close to Vatican and other attractions. Hotel is historic structure built in the 1500s. It was refurbished appt 1970 and has all the modern features a traveler would want. Staff is very accommodating and helpful. Lots of restaurants are close by. Would stay there again.
Hotel is convenient as to is very close to Vatican and other attractions. Hotel is historic structure built in the 1500s. It was refurbished appt 1970 and has all the modern features a traveler would want. Staff is very accommodating and helpful. Lots of restaurants are close by. Would stay there again.
10
Christopher
Apr 1, 2024
·
Stayed 3 nights
Friendly, accommodating staff. A few minutes walk to the Vatican. Perfect location! Very nice, quiet patio area
Friendly, accommodating staff. A few minutes walk to the Vatican. Perfect location! Very nice, quiet patio area
8
Steven
Oct 23, 2024
·
Stayed 3 nights
Loved the area at night. Perfect place to stay. Easy to get to all of the sites. Staff was really nice. Breakfast was amazing. Only hiccup for us was checking out the elevator was being used by staff so we had to carry heavy luggage down two flights of stairs. But other than that it was excellent.
Loved the area at night. Perfect place to stay. Easy to get to all of the sites. Staff was really nice. Breakfast was amazing. Only hiccup for us was checking out the elevator was being used by staff so we had to carry heavy luggage down two flights of stairs. But other than that it was excellent.
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AI-generated summary based on recent guest reviews
Cleanliness
Many guests describe the hotel and rooms as very clean, with daily tidying noted in several stays. A few mention minor wear or isolated housekeeping lapses.
Related guest reviews
10
Julia
Jan 22, 2025
·
Stayed 1 night
We adored our short stay! The staff was so friendly and hospitable. They allowed us to store our bags for a few hours after check-out when our flight out of Rome got delayed, which was greatly appreciated. The room itself was clean and well-appointed with a comfortable bed, and the bathroom was modern! The hotel itself had a lot of character and was close to the Vatican and tons of restaurants and shops. Grazie mille!
We adored our short stay! The staff was so friendly and hospitable. They allowed us to store our bags for a few hours after check-out when our flight out of Rome got delayed, which was greatly appreciated. The room itself was clean and well-appointed with a comfortable bed, and the bathroom was modern! The hotel itself had a lot of character and was close to the Vatican and tons of restaurants and shops. Grazie mille!
10
michael
Jan 2, 2024
·
Stayed 1 night
Great spot to crash for the night. Breakfast was good for $10 E each. Staff was very friendly. Bathroom was very nice. Could have been cleaner. Happy overall.
Great spot to crash for the night. Breakfast was good for $10 E each. Staff was very friendly. Bathroom was very nice. Could have been cleaner. Happy overall.
10
Jeffrey
Jun 19, 2024
·
Stayed 1 night
The perfect location for Vatican City tours. Spacious, clean room and friendly staff. Would definitely stay here again.
The perfect location for Vatican City tours. Spacious, clean room and friendly staff. Would definitely stay here again.
10
Lynn
Jun 10, 2025
·
Stayed 2 nights
Great little hotel very near the Vatican. Very clean and typically Roman. Lovely.
Great little hotel very near the Vatican. Very clean and typically Roman. Lovely.
10
Thomas
Aug 15, 2024
·
Stayed 3 nights
Clean, quiet room, comfortable bed and shower, friendly helpful staff very knowledgeable of area with good advice, convenient walking distance to Vatican and to restaurants and souvenir shops, short ride to other key sites, Elisabetta at front desk was especially helpful.
Clean, quiet room, comfortable bed and shower, friendly helpful staff very knowledgeable of area with good advice, convenient walking distance to Vatican and to restaurants and souvenir shops, short ride to other key sites, Elisabetta at front desk was especially helpful.
10
Janelle
Dec 14, 2023
·
Stayed 3 nights
The place to stay if you plan on going to Rome. Located in a prime location right next to the Vatican and quick taxi rides to the Colosseum, Pantheon, etc. Staff are friendly from arrival to departure, professional and helpful. Rooms are exceptional, spacious, and clean!
The place to stay if you plan on going to Rome. Located in a prime location right next to the Vatican and quick taxi rides to the Colosseum, Pantheon, etc. Staff are friendly from arrival to departure, professional and helpful. Rooms are exceptional, spacious, and clean!
10
John
Nov 6, 2025
·
Stayed 8 nights
Rooms were immaculate, staff were courteous, breakfast was wonderful.
Rooms were immaculate, staff were courteous, breakfast was wonderful.
10
Patricia and Charles
Sep 27, 2025
·
Stayed 3 nights
Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful. The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.
Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful. The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.
10
Barry A
Sep 11, 2025
·
Stayed 9 nights
Extremely nice and helpful staff. Room was very quaint and great access to a lot of tourist spots within a mile. Room was cleaned every day. Highly recommend
Extremely nice and helpful staff. Room was very quaint and great access to a lot of tourist spots within a mile. Room was cleaned every day. Highly recommend
10
Robert
Nov 21, 2023
·
Stayed 9 nights
Es ist ein super sauberes und sehr freundliches kleines Hotel am Rande des Vatikans, der zu Fuß in ca. 3Minuten und die Engelsburg in ca. 10 Minuten erreichbar ist. Das Personal ist sehr freundlich und die Bäder wurden modernisiert. Wir waren jetzt zum zweiten Mal dort und kommen gerne immer wieder in dieses Hotel, das wirklich sehr zu empfehlen ist!
Es ist ein super sauberes und sehr freundliches kleines Hotel am Rande des Vatikans, der zu Fuß in ca. 3Minuten und die Engelsburg in ca. 10 Minuten erreichbar ist. Das Personal ist sehr freundlich und die Bäder wurden modernisiert. Wir waren jetzt zum zweiten Mal dort und kommen gerne immer wieder in dieses Hotel, das wirklich sehr zu empfehlen ist!
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AI-generated summary based on recent guest reviews
Rooms
Rooms are comfortable, often larger than typical for Rome and attractively decorated, with some charming historic details. Several reviews report seasonal AC shutoffs leading to warm nights and street noise when windows are open; a few mention firm beds.
Related guest reviews
10
Bora
Sep 12, 2023
·
Stayed 5 nights
Awesome location. Rooms were big and plenty of space. Hard to find this big of a room in an European hotel. Plenty of great restaurants on the same street. We are coming back to Rome in 3 months and will definitely stay here again.
Awesome location. Rooms were big and plenty of space. Hard to find this big of a room in an European hotel. Plenty of great restaurants on the same street. We are coming back to Rome in 3 months and will definitely stay here again.
10
Richard
Jan 2, 2025
·
Stayed 3 nights
Best room we've had in my entire 11 nights tour in Italy where we stayed in 5 other hotels before arriving at Sant' Anna hotel. Size of room was big (relative to the other rooms elsewhere), and the room deco had a "wow" effect when we opened the door. Best of all, lots of table space to place luggage, lots of clothes hangers and functional amenities. Though its elevator was small, the other hotels we went to elsewhere was equally small though it is not as ancient as Sant' Anna. Its proximity to Vatican and the shopping areas was excellent.
Best room we've had in my entire 11 nights tour in Italy where we stayed in 5 other hotels before arriving at Sant' Anna hotel. Size of room was big (relative to the other rooms elsewhere), and the room deco had a "wow" effect when we opened the door. Best of all, lots of table space to place luggage, lots of clothes hangers and functional amenities. Though its elevator was small, the other hotels we went to elsewhere was equally small though it is not as ancient as Sant' Anna. Its proximity to Vatican and the shopping areas was excellent.
10
Valerie
May 13, 2024
·
Stayed 2 nights
Great location! Just a short walk to Vatican. Believe our room was upgraded to include a balcony! Faced pedestrian street but very quiet! Great restaurant options on pedestrian street. When used to sleeping with a bed topper, did find bed a little hard at first, but once asleep, didn’t notice it! Great breakfast with all we needed. Service at front desk was awesome!
Great location! Just a short walk to Vatican. Believe our room was upgraded to include a balcony! Faced pedestrian street but very quiet! Great restaurant options on pedestrian street. When used to sleeping with a bed topper, did find bed a little hard at first, but once asleep, didn’t notice it! Great breakfast with all we needed. Service at front desk was awesome!
4
Thanh
May 3, 2025
·
Stayed 1 night
The air conditioning was not on. We were asked to sleep with an open window as it is what it is. The hotel shut down air conditioner. I opened the window and the noise from restaurants below was unbearable to sleep. We could not sleep through the night, the room was so hot. I was disappointed to pay premium for a motel condition.
The air conditioning was not on. We were asked to sleep with an open window as it is what it is. The hotel shut down air conditioner. I opened the window and the noise from restaurants below was unbearable to sleep. We could not sleep through the night, the room was so hot. I was disappointed to pay premium for a motel condition.
10
Koki
Oct 4, 2025
·
Stayed 2 nights
バチカン近くで観光にちょうどいい。ローマ観光中心地へは20分程度でいけるので問題なし。 部屋は広くて快適。エアコンが個室調整できないようだが、大きな問題ではない。
バチカン近くで観光にちょうどいい。ローマ観光中心地へは20分程度でいけるので問題なし。 部屋は広くて快適。エアコンが個室調整できないようだが、大きな問題ではない。
8
Sidney
Feb 20, 2024
·
Stayed 4 nights
This is a small hotel with nice rooms but not a lot of options. There were very few rooms with bathtubs.Rooms were on the small side and despite being a little warm outside, there was no AC option. We had to open the window. The staff was very friendly and the breakfast was wonderful.
This is a small hotel with nice rooms but not a lot of options. There were very few rooms with bathtubs.Rooms were on the small side and despite being a little warm outside, there was no AC option. We had to open the window. The staff was very friendly and the breakfast was wonderful.
8
Peter
May 4, 2023
·
Stayed 6 nights
Though the street is pedestrianised it is sometimes noisy. Air con as with other hotels in Italy is not available during the Spring so an open window means sleeping is not so easy. The plus is a fantastic location near the Vatican. We preferred to go out for breakfast rather than the hotel offering in the basement, though that was perfectly adequate.
Though the street is pedestrianised it is sometimes noisy. Air con as with other hotels in Italy is not available during the Spring so an open window means sleeping is not so easy. The plus is a fantastic location near the Vatican. We preferred to go out for breakfast rather than the hotel offering in the basement, though that was perfectly adequate.
8
Michael
Apr 17, 2025
·
Stayed 1 night
We booked this hotel as it was close to Vatican City and was a recommendation. We enjoyed the hotel. No restaurant or bar but they exist in abundance within walking distance. The one issue for us was no AC and we were facing the busy pedestrian/cafe area and had to keep window open but lights and noise were an issue. Desk staff was very helpful giving directions and scheduling a car for us.
We booked this hotel as it was close to Vatican City and was a recommendation. We enjoyed the hotel. No restaurant or bar but they exist in abundance within walking distance. The one issue for us was no AC and we were facing the busy pedestrian/cafe area and had to keep window open but lights and noise were an issue. Desk staff was very helpful giving directions and scheduling a car for us.
8
Jennifer
May 9, 2025
·
Stayed 6 nights
Nice hotel in a prime location. Staff were friendly and helpful. It was warm when we were there and we couldn't turn on the AC due to regulations. We will return to this hotel but only during the cooler months.
Nice hotel in a prime location. Staff were friendly and helpful. It was warm when we were there and we couldn't turn on the AC due to regulations. We will return to this hotel but only during the cooler months.
10
Christine
Oct 20, 2025
·
Stayed 2 nights
Wonderful room and fantastic location.
Wonderful room and fantastic location.
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AI-generated summary based on recent guest reviews
Service
Service is consistently praised as friendly, professional, and helpful, with staff assisting with directions, transport, and luggage.
Related guest reviews
10
Julia
Jan 22, 2025
·
Stayed 1 night
We adored our short stay! The staff was so friendly and hospitable. They allowed us to store our bags for a few hours after check-out when our flight out of Rome got delayed, which was greatly appreciated. The room itself was clean and well-appointed with a comfortable bed, and the bathroom was modern! The hotel itself had a lot of character and was close to the Vatican and tons of restaurants and shops. Grazie mille!
We adored our short stay! The staff was so friendly and hospitable. They allowed us to store our bags for a few hours after check-out when our flight out of Rome got delayed, which was greatly appreciated. The room itself was clean and well-appointed with a comfortable bed, and the bathroom was modern! The hotel itself had a lot of character and was close to the Vatican and tons of restaurants and shops. Grazie mille!
10
Stephen
Sep 22, 2025
·
Stayed 4 nights
Wonderful location, very helpful service and staff!
Wonderful location, very helpful service and staff!
10
Norma
Mar 21, 2025
·
Stayed 1 night
The staff was very courteous and helpful. They also called an excellent taxi service to take us to the airport. The best we had all Of the trip. I would highly recommend to stay here. The rooms were great and the breakfast was also very filling with several options.
The staff was very courteous and helpful. They also called an excellent taxi service to take us to the airport. The best we had all Of the trip. I would highly recommend to stay here. The rooms were great and the breakfast was also very filling with several options.
10
Cherry
Oct 20, 2025
·
Stayed 1 night
Very hospitable front desk staff. Will be staying here from now on everytime Rome tugs at my heartstrings!
Very hospitable front desk staff. Will be staying here from now on everytime Rome tugs at my heartstrings!
10
Danilo
Dec 4, 2024
·
Stayed 1 night
It is excellent as we are still here. However, the hotel front desk representative/s i dealt with were very professional and friendly. We were provided with accurate information and details of what i requested or asked for. I was also informed to adjust my hotel hired driver pickup time to have more time to go to the airport for our international flight.home. It was an excellent suggestion.
It is excellent as we are still here. However, the hotel front desk representative/s i dealt with were very professional and friendly. We were provided with accurate information and details of what i requested or asked for. I was also informed to adjust my hotel hired driver pickup time to have more time to go to the airport for our international flight.home. It was an excellent suggestion.
10
Thomas
Aug 15, 2024
·
Stayed 3 nights
Clean, quiet room, comfortable bed and shower, friendly helpful staff very knowledgeable of area with good advice, convenient walking distance to Vatican and to restaurants and souvenir shops, short ride to other key sites, Elisabetta at front desk was especially helpful.
Clean, quiet room, comfortable bed and shower, friendly helpful staff very knowledgeable of area with good advice, convenient walking distance to Vatican and to restaurants and souvenir shops, short ride to other key sites, Elisabetta at front desk was especially helpful.
10
Mark
Oct 29, 2023
·
Stayed 4 nights
We were very happy with our accommodations. Clean with excellent desk service. In fact. The desk service was super. Arrangements for taxi's and general information was much better than I ever expected. I think the highest compliment I can make is that we would stay there again. No reservations about a return visit.
We were very happy with our accommodations. Clean with excellent desk service. In fact. The desk service was super. Arrangements for taxi's and general information was much better than I ever expected. I think the highest compliment I can make is that we would stay there again. No reservations about a return visit.
10
Thomas
Aug 25, 2024
·
Stayed 5 nights
This location is perfect for all of Rome's attractions. A few sort steps to the Vatican and St. Peter's Square with an amazing assortment of restaurants sure to exceed your expectations! Clean, quiet and amazing service to help you get the most out of your holiday. Elizabeth was exceptional at arrangements and was extremely helpful! As your day in Rome ends make sure you stop right next door for the best Gelato to take back to your room!
This location is perfect for all of Rome's attractions. A few sort steps to the Vatican and St. Peter's Square with an amazing assortment of restaurants sure to exceed your expectations! Clean, quiet and amazing service to help you get the most out of your holiday. Elizabeth was exceptional at arrangements and was extremely helpful! As your day in Rome ends make sure you stop right next door for the best Gelato to take back to your room!
10
Patricia and Charles
Sep 27, 2025
·
Stayed 3 nights
Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful. The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.
Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful. The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.
10
Barry A
Sep 11, 2025
·
Stayed 9 nights
Extremely nice and helpful staff. Room was very quaint and great access to a lot of tourist spots within a mile. Room was cleaned every day. Highly recommend
Extremely nice and helpful staff. Room was very quaint and great access to a lot of tourist spots within a mile. Room was cleaned every day. Highly recommend
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AI-generated summary based on recent guest reviews
Location
Excellent position steps from St. Peter’s on pedestrian Borgo Pio, surrounded by restaurants and shops, with the metro and other sights walkable. Some note street buzz or hawkers outside.
Related guest reviews
10
Charles
May 22, 2024
·
Stayed 5 nights
Excellent location and very quiet.
Excellent location and very quiet.
10
Beata
Mar 5, 2024
·
Stayed 2 nights
Beautifully decorated rooms with close location to metro and top attractions of Rome.
Beautifully decorated rooms with close location to metro and top attractions of Rome.
10
Kera
Jun 12, 2024
·
Stayed 3 nights
Very conveniently located near the Vatican for the early morning tour we were doing. It was also a reasonable walk to the Trevi fountain area (but it wasn’t close). Hotel had air conditioning which was great for the warm weather. Many restaurants located right on the street outside the hotel. Check in was easy. Room was very comfortable and clean. We enjoyed our stay for 3 nights.
Very conveniently located near the Vatican for the early morning tour we were doing. It was also a reasonable walk to the Trevi fountain area (but it wasn’t close). Hotel had air conditioning which was great for the warm weather. Many restaurants located right on the street outside the hotel. Check in was easy. Room was very comfortable and clean. We enjoyed our stay for 3 nights.
10
Linda
Mar 31, 2025
·
Stayed 3 nights
Excellent location to walk to the Vatican, Castel Sant'Angelo and even across the bridge of the river Tiber. Right next to many delicious restaurants, Gelato and pizza. McDonalds is right on the corner which makes it a great location for Uber pick up. Rooms are nice and spacious enough.
Excellent location to walk to the Vatican, Castel Sant'Angelo and even across the bridge of the river Tiber. Right next to many delicious restaurants, Gelato and pizza. McDonalds is right on the corner which makes it a great location for Uber pick up. Rooms are nice and spacious enough.
10
Thomas
Aug 25, 2024
·
Stayed 5 nights
This location is perfect for all of Rome's attractions. A few sort steps to the Vatican and St. Peter's Square with an amazing assortment of restaurants sure to exceed your expectations! Clean, quiet and amazing service to help you get the most out of your holiday. Elizabeth was exceptional at arrangements and was extremely helpful! As your day in Rome ends make sure you stop right next door for the best Gelato to take back to your room!
This location is perfect for all of Rome's attractions. A few sort steps to the Vatican and St. Peter's Square with an amazing assortment of restaurants sure to exceed your expectations! Clean, quiet and amazing service to help you get the most out of your holiday. Elizabeth was exceptional at arrangements and was extremely helpful! As your day in Rome ends make sure you stop right next door for the best Gelato to take back to your room!
10
Patricia and Charles
Sep 27, 2025
·
Stayed 3 nights
Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful. The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.
Hotel Sant ‘Anna is in a great location close to Vatican City, the metro, and many restaurants & tourist shops. We were comfortable and had space for our family of four. The hotel is nice, clean, quiet, and comfortable. The staff was friendly and helpful. The only downside was the annoyance of having to walk past the restaurants hawkers (with their high-pressure sales pitch to lure in you and others) who on the street in front of the hotel, but that was the trade-off for convenience.
10
chris
Mar 13, 2024
·
Stayed 4 nights
Lovely comfortable hotel on quiet pedestrian only street, literally just a few steps away from the Vatican with great restaurants all around. we had a lovely first stay in Italy.
Lovely comfortable hotel on quiet pedestrian only street, literally just a few steps away from the Vatican with great restaurants all around. we had a lovely first stay in Italy.
10
Christine
Oct 20, 2025
·
Stayed 2 nights
Wonderful room and fantastic location.
Wonderful room and fantastic location.
10
John
Apr 1, 2025
·
Stayed 4 nights
Our stay for the Jubilee 2015 was wonderful! The hotel is a 5 minute walk to St. Peter’s Basilica and a short walk to the Vatican Museum.
Our stay for the Jubilee 2015 was wonderful! The hotel is a 5 minute walk to St. Peter’s Basilica and a short walk to the Vatican Museum.
10
Elizabeth
May 1, 2023
·
Stayed 3 nights
Friendly staff, during day/evening street buzzing with cafes, but quiet overnight. Location to Vatican fantastic.
Friendly staff, during day/evening street buzzing with cafes, but quiet overnight. Location to Vatican fantastic.
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AI-generated summary based on recent guest reviews
Dining
Breakfast is widely appreciated for quality, eggs and pastries, though a few guests considered it average.
Related guest reviews
8
Elizabeth
Sep 14, 2024
·
Stayed 3 nights
Great breakfast! Friendly staff. Bright and clean room.
Great breakfast! Friendly staff. Bright and clean room.
6
Stephen
Jul 20, 2024
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Stayed 1 night
Hotel 5 mins from Vatican. Good hotel but could Do with a bit of internal redecoration. Staff excellent, breakfast ok but not great. It’s the kind of place your local Priest would stay while in Rome to show parishioners he is not on a jolly!
Hotel 5 mins from Vatican. Good hotel but could Do with a bit of internal redecoration. Staff excellent, breakfast ok but not great. It’s the kind of place your local Priest would stay while in Rome to show parishioners he is not on a jolly!
10
DIANE
Jul 24, 2025
·
Stayed 2 nights
This hotel is very quaint near everything to walk. The front desk was very nice and helpful and polite. Nice breakfast in the morning too. I would definitely stay here again.
This hotel is very quaint near everything to walk. The front desk was very nice and helpful and polite. Nice breakfast in the morning too. I would definitely stay here again.
10
Kendra
May 11, 2025
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Stayed 4 nights
Wonderful stay in a fabulous location! Welcoming and friendly staff were most accommodating and helpful with our needs and questions. Well-appointed rooms. Delicious buffet breakfast. Great restaurant and gelato vendor on either side of the lovely entrance. We can’t wait to return for a repeat stay!
Wonderful stay in a fabulous location! Welcoming and friendly staff were most accommodating and helpful with our needs and questions. Well-appointed rooms. Delicious buffet breakfast. Great restaurant and gelato vendor on either side of the lovely entrance. We can’t wait to return for a repeat stay!
10
Gary
Apr 28, 2024
·
Stayed 1 night
We were happily surprised with hotel. Great with party larger than 2. Bedroom we stayed in had two twins and a queen. Perfect for us. I had little expectations on the breakfast, but the scrambled eggs made fresh in the kitchen may be the best I have ever tasted & pastries were excellent! We will utilize again in Rome. Perfect location if Vatican is a priority.
We were happily surprised with hotel. Great with party larger than 2. Bedroom we stayed in had two twins and a queen. Perfect for us. I had little expectations on the breakfast, but the scrambled eggs made fresh in the kitchen may be the best I have ever tasted & pastries were excellent! We will utilize again in Rome. Perfect location if Vatican is a priority.
8
Peter
May 4, 2023
·
Stayed 6 nights
Though the street is pedestrianised it is sometimes noisy. Air con as with other hotels in Italy is not available during the Spring so an open window means sleeping is not so easy. The plus is a fantastic location near the Vatican. We preferred to go out for breakfast rather than the hotel offering in the basement, though that was perfectly adequate.
Though the street is pedestrianised it is sometimes noisy. Air con as with other hotels in Italy is not available during the Spring so an open window means sleeping is not so easy. The plus is a fantastic location near the Vatican. We preferred to go out for breakfast rather than the hotel offering in the basement, though that was perfectly adequate.
10
John
Nov 6, 2025
·
Stayed 8 nights
Rooms were immaculate, staff were courteous, breakfast was wonderful.
Rooms were immaculate, staff were courteous, breakfast was wonderful.
10
Doreen
Aug 6, 2023
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Stayed 2 nights
Excellent location for visiting the Vatican. It is a quaint place to stay, with super helpful staff. The breakfast was absolutely delicious, the best scrambled eggs I have ever had! The beds were quite firm. I would definitely stay here again the next time visiting Rome. It is on a street generally closed to traffic with lots of restaurants and shops, so it’s super convenient for most anything you might need. A 2 block walk and you are entering St Peters Square. Really loved it! It is also an easy walk for other sites as well.
Excellent location for visiting the Vatican. It is a quaint place to stay, with super helpful staff. The breakfast was absolutely delicious, the best scrambled eggs I have ever had! The beds were quite firm. I would definitely stay here again the next time visiting Rome. It is on a street generally closed to traffic with lots of restaurants and shops, so it’s super convenient for most anything you might need. A 2 block walk and you are entering St Peters Square. Really loved it! It is also an easy walk for other sites as well.
10
Daniel
Aug 1, 2023
·
Stayed 1 night
Perfect location! Only two blocks away from St. Peter's Square with several great restaurants within walking distance. Room was clean and comfortable. Staff was friendly and helpful with local attractions, restaurant options, and tips getting around. Also, best gelato in Rome is next door.
Perfect location! Only two blocks away from St. Peter's Square with several great restaurants within walking distance. Room was clean and comfortable. Staff was friendly and helpful with local attractions, restaurant options, and tips getting around. Also, best gelato in Rome is next door.
10
John
Aug 23, 2025
·
Stayed 5 nights
All of the staffs were amazing. We stayed for 5 nights and no complaints at all. Breakfast was great. This is the hotel
All of the staffs were amazing. We stayed for 5 nights and no complaints at all. Breakfast was great. This is the hotel
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AI-generated summary based on recent guest reviews
10
Renata
3 weeks ago
·
Stayed 4 nights
Great location and very nice staff
Great location and very nice staff
10
Pam Podgorski Vanderhoof
Aug 2, 2026
·
Stayed 2 nights
Great location by Vatican City on St Peter's side- great restaurants and coffee pastry and awesome gelato next door or within a block radius . Great price- customer service outstanding- clean rooms and clean building - Highly recommend
Great location by Vatican City on St Peter's side- great restaurants and coffee pastry and awesome gelato next door or within a block radius . Great price- customer service outstanding- clean rooms and clean building - Highly recommend
10
Luis
Jul 26, 2026
·
Stayed 4 nights
Highly recommend. Were a family of four, so size and accommodations were perfect. Staff really nice and it is short walk from Vatican and a lovely longer one to all Rome’s treasures!!
Highly recommend. Were a family of four, so size and accommodations were perfect. Staff really nice and it is short walk from Vatican and a lovely longer one to all Rome’s treasures!!
10
Julie
Jul 16, 2026
·
Stayed 1 night
Very easy and pleasant. Close to everything
Very easy and pleasant. Close to everything
10
Orion
Jun 12, 2026
·
Stayed 4 nights
The rooms are very clean and spacious. The coffee and tea making was definitely a big plus for us. We did not eat breakfast at the hotel as we had early tours booked. There are great restaurants in the hotel street. We tried 6 of them and they were all had amazing food.
The rooms are very clean and spacious. The coffee and tea making was definitely a big plus for us. We did not eat breakfast at the hotel as we had early tours booked. There are great restaurants in the hotel street. We tried 6 of them and they were all had amazing food.
FAQs about Hotel S. Anna
What type of breakfast is offered and what are the serving hours?
Buffet breakfasts are available daily from 7:00 AM to 10:00 AM for a fee of approximately EUR 15 per person.
What are the check-in and check-out times?
Check-in is from 1:30 PM until midnight, and check-out is until 10:30 AM. Early or late check-in/check-out may be available upon request.
What is the hotel's location in relation to key landmarks?
The hotel is centrally located in Rome, just a 3-minute walk from St. Peter's Square and 8 minutes by foot from St. Peter's Basilica. It is also 0.7 mi (1.1 km) from Vatican Museums and 0.3 mi (0.5 km) from Sistine Chapel.
What are the hotel's policies regarding children?
Children are allowed at the property, but specific age policies for free stays are not provided.
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Prices for upcoming dates
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Average nightly price across deals, with taxes & fees.
Prices in USD for 2 guests, updated daily.
- 2026-09-30: NO DATA
- 2026-10-01: 281.68765828111265USD
- 2026-10-02: NO DATA
- 2026-10-03: 293.8730511352844USD
- 2026-10-04: 292.4381644168396USD
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- 2026-10-15: NO DATA
- 2026-10-16: 307.50060614163203USD
- 2026-10-17: NO DATA
- 2026-10-18: NO DATA
- 2026-10-19: 275.88473809986874USD
- 2026-10-20: NO DATA
- 2026-10-21: NO DATA
- 2026-10-22: NO DATA
- 2026-10-23: NO DATA
- 2026-10-24: 309.13030329739377USD
- 2026-10-25: NO DATA
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- 2026-10-27: NO DATA
- 2026-10-28: NO DATA
- 2026-10-29: NO DATA
- 2026-10-30: NO DATA
- 2026-10-31: 302.5526264577942USD
- 2026-11-01: 284.85581009431456USD
- 2026-11-02: NO DATA
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- 2026-11-04: NO DATA
- 2026-11-05: NO DATA
- 2026-11-06: NO DATA
- 2026-11-07: 252.1400163030853USD
- 2026-11-08: 236.0005707247467USD
- 2026-11-09: 252.4169792262268USD
- 2026-11-10: NO DATA
- 2026-11-11: NO DATA
- 2026-11-12: NO DATA
- 2026-11-13: 218.28206500941465USD
- 2026-11-14: 205.27365797291563USD
- 2026-11-15: 207.762660886322USD
- 2026-11-16: 212.0492779660034USD
- 2026-11-17: 199.9894676573639USD
- 2026-11-18: 213.3431753380737USD
- 2026-11-19: 203.43653392181395USD
- 2026-11-20: NO DATA
- 2026-11-21: NO DATA
- 2026-11-22: NO DATA
- 2026-11-23: 213.28391051083372USD
- 2026-11-24: 219.2989994583435USD
- 2026-11-25: 205.01686084020994USD
- 2026-11-26: 244.12859969577025USD
- 2026-11-27: NO DATA
- 2026-11-28: NO DATA
- 2026-11-29: 236.41624621147153USD
- 2026-11-30: 200.51293939398192USD
If you are planning to arrive after midnight please contact the property in advance using the information on the booking confirmation. Front desk staff will greet guests on arrival at the property. For any questions, please contact the property using the information on the booking confirmation. Information provided by the property may be translated using automated translation tools. Guests staying at the apartments should go the hotel's main address to check in.
Check-in must be done by someone who is at least 18 years old.
- Extra-person charges may apply and vary depending on property policy
- Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
- Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
- This property accepts credit cards, debit cards, and cash
- Safety features at this property include a carbon monoxide detector, a fire extinguisher, and a smoke detector
- Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
- All guests, including children, must be present at check-in and show their government-issued photo ID card or passport.
- Cash transactions at this property cannot exceed EUR 5000, due to national regulations. For further details, please contact the property using information in the booking confirmation.
- Only registered guests are allowed in the guestrooms.
- Fee for buffet breakfast: approximately EUR 15 per person
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
Popular amenities
Airport shuttle
Non-Smoking Rooms
Housekeeping
Safe-Deposit Box
Garden
Luggage Storage
Services
Housekeeping
Safe-Deposit Box
Luggage Storage
Express Check-In/Check-Out
24-Hour Front Desk
Concierge Services
General
Non-Smoking Rooms
Family Room
Activities
Garden
Outdoor Furniture
Parking
Airport shuttle
Internet
Free Wi-Fi