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Residence Inn By Marriott Jacksonville-Mayo Clinic Area




Residence Inn By Marriott Jacksonville-Mayo Clinic Area - Image 1
Residence Inn By Marriott Jacksonville-Mayo Clinic Area - Room
Residence Inn By Marriott Jacksonville-Mayo Clinic Area - Room
Residence Inn By Marriott Jacksonville-Mayo Clinic Area - Reception
Residence Inn By Marriott Jacksonville-Mayo Clinic Area - Pool

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About this property

Be sure to enjoy recreational amenities including an outdoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, concierge services, and wedding services.
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  • Parking

  • Swimming pool

  • Non-Smoking Rooms

  • Business Center

  • Dry Cleaning

  • Housekeeping

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Location

4905 San Pablo Road South, Isle of Palms, Jacksonville Beach, Florida, United States of America

Mayo Clinic Florida (0.9 Miles)

Windsor Commons Shopping Center (2.4 Miles)

Windsor Parke Golf Club (3.2 Miles)

South Beach Park and Sunshine Playground (4 Miles)

Atlantic Beach (4.4 Miles)

Jacksonville Beach Tennis Center (4.4 Miles)


Guest reviews

Facilities

9.2

Cleanliness

9.6

Service

9.6

8

arthur

IAN-logo

20 May 2026

·

Stayed 2 nights

People working on their cars in car park. Unexplained charges made on card after checking out and leaving area
People working on their cars in car park. Unexplained charges made on card after checking out and leaving area

10

Robin

IAN-logo

12 May 2026

·

Stayed 2 nights

Very clean hotel and nice room. Great breakfast included. Very close to Mayo but not on campus. There used to be a shuttle! I would recommend.
Very clean hotel and nice room. Great breakfast included. Very close to Mayo but not on campus. There used to be a shuttle! I would recommend.

8

Elisa

IAN-logo

10 May 2026

·

Stayed 2 nights

Very clean Staff friendly and helpful Bed is pretty hard I prefer softer Otherwise everything else's great
Very clean Staff friendly and helpful Bed is pretty hard I prefer softer Otherwise everything else's great

10

Pam

IAN-logo

8 May 2026

·

Stayed 1 night

Did not eat there
Did not eat there

10

Melody

IAN-logo

3 May 2026

·

Stayed 2 nights

We enjoyed our stay. Breakfast was good and stocked well. Love the proximity to Mayo Clinic.
We enjoyed our stay. Breakfast was good and stocked well. Love the proximity to Mayo Clinic.

Property policies

Check-in instructions

Everything you need to know for a smooth check-in.

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Check-in

Check-out

From 16:00 to 06:00

Before 11:00


Security deposit

You'll be required to pay the fully refundable deposit for this property.

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Good to know

Additional policies and info about this property.

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Optional extras

Additional paid services you can request.

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FAQs

Yes, free self-parking is available on-site. However, parking is limited.


A complimentary buffet breakfast is served on weekdays from 6:30 AM to 9:00 AM and on weekends from 7:00 AM to 9:30 AM.


Yes, pets are allowed with a fee of USD 150 per accommodation, per stay. Service animals are exempt from fees.


Check-in is from 4:00 PM to 11:00 PM, and check-out is by 11:00 AM. Early or late check-in/check-out may be available upon request and could incur additional charges.


The property offers limited wheelchair accessibility, including step-free entrances and accessible facilities in public areas. However, specific details should be confirmed directly with the property.

The hotel is located in Jacksonville (Isle of Palms), just a 3-minute drive from Mayo Clinic Florida and 9 minutes from St. Johns Town Center. It is approximately 10.3 miles from Mayport Naval Station and 5.2 miles from the University of North Florida.


Yes, there is an outdoor heated pool available for guests. The pool is operational seasonally.


Children are welcome at the property. The minimum age for children to stay for free is not specified, so it is advisable to check with the property directly for details.


The property does not specify the availability of extra beds or cribs. It is recommended to contact the property directly for information regarding extra sleeping arrangements.


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