Hotels with non-smoking rooms near Mission, San Francisco

Luxury hotel in the heart of San Francisco with a 24-hour fitness center and multiple dining options.

Centrally located hotel with indoor pool, hot tub, and on-site dining in San Francisco's vibrant SoMa district.

Comfortable hotel in the heart of San Francisco with convenient amenities and on-site dining options.

Luxury hotel with a 24-hour fitness center, on-site dining, and close proximity to the San Francisco Museum of Modern Art.

Luxury hotel with an indoor pool, two restaurants, and a business center in the heart of San Francisco.

Centrally located hotel with a restaurant, fitness center, and modern rooms featuring flat-screen TVs and refrigerators.

Stay in the heart of San Francisco with a fitness center, bicycle rentals, and a complimentary breakfast at this modern hotel.

Boutique hotel with a restaurant, 24-hour fitness center, and modern rooms near San Francisco Museum of Modern Art.

Luxury hotel in the heart of San Francisco with a spa, swimming pool, and fine dining restaurant.

Luxury hotel with indoor pool, on-site restaurant, and exceptional service in the heart of San Francisco.

Comfortable inn in the heart of San Francisco with air-conditioned rooms and complimentary breakfast.

Comfortable motel in San Francisco with free parking, complimentary Wi-Fi, and convenient access to local attractions.

Budget-friendly motel with convenient amenities and a 24-hour front desk in downtown San Francisco.

Budget-friendly hostel with shared kitchen, terrace views, and convenient access to downtown San Francisco attractions.

Cozy inn in downtown San Francisco with shared bathrooms and convenient access to local attractions.

Comfortable motel in San Francisco with free parking, complimentary breakfast, and air-conditioned rooms with LED TVs.

Convenient hotel in downtown San Francisco with complimentary wifi and easy access to Union Square and Bill Graham Civic Auditorium.

Modern hotel in the heart of San Francisco with a 24-hour fitness center and terrace views.